Generic Name: Ulinastatin for Injection Trademark: The Kangyuan
Pharmaceutical Company
Ulinastatin character
This product is a white to yellowish freeze-dried lump or powder. After
reconstitution, it shall be a clear liquid, colorless to yellow, with slight
opalescence.
Ulinastatin is pharmacologically and toxicologically
This strain is a refined glycoprotein extracted from human urine and
belongs to protease inhibitor. It can inhibit the activity of trypsin and other
trypsin, and is often used in the treatment of pancreatitis. In addition, this
product also has the function of stabilizing lysosomal membrane, inhibiting the
release of lysosomal enzyme and inhibiting the production of myocardial
inhibitory factors, so it can be used in the rescue treatment of acute
circulatory failure.
The pharmacokinetics of ulinastatin
After intravenous injection of 300,000 units /10ml in healthy normal men,
the blood drug concentration decreased sharply within 3 hours, and the clearance
half-life was 40 minutes. 24% of the dose administered was excreted in the urine
six hours after administration.