Industry Information

A comprehensive introduction to Urofollitropin

  Introduction to Urofollitropin: Follicle-stimulating hormone, also known as follicle-stimulating hormone (Follicle-stimulating Hormone, FSH), is a gonadotropin secreted by basophils in the anterior pituitary gland, and its composition is a glycoprotein.

  Secretion mode: It is secreted in pulses in the human body, and women change with the menstrual cycle.

  Function: The main function of FSH is to proliferate granulosa cells, differentiate endometrial cells, form follicular fluid, and expand the follicular cavity, so as to make follicles grow and develop, improve the efficiency of mature follicles, and then increase ovulation rate and pregnancy rate.

A comprehensive introduction to Urofollitropin

  For women: the main function is to promote the maturation of follicles. It can promote the proliferation and differentiation of follicular granulosa cells, and promote the growth of the entire ovary.

  For men: It acts on the seminiferous tubules of the testis to promote sperm formation.

  Currently, the indications for follicle-stimulating hormones approved in China are:

  (1) For anovulation (including polycystic ovary syndrome, PCOS) who are ineffective after receiving clomiphene citrate treatment;

  (2) Used in assisted reproductive technology (such as in vitro fertilization-embryo transfer (IVF-ET), gamete intrafallopian transfer

  (GIFT) and intracytoplasmic sperm injection (ICSI)) in order to achieve the purpose of multiple follicular developments

  Clinical significance: Determining Urofollitropin in serum is of great significance for understanding pituitary endocrine function, indirectly understanding the functional status of the hypothalamus and ovary, predicting ovulation time, infertility, and diagnosis and treatment of endocrine diseases.