Industry Information

Urofollitropin product usage process

  Follicle-stimulating hormone (follicle-stimulating hormone, FSH) is a glycoprotein gonadotropin synthesized and secreted by basophils in the anterior pituitary gland, controlled by a follicle-stimulating hormone-releasing hormone secreted by the hypothalamus. FSH has the functions of regulating the growth, sexual maturity, and reproduction of the body, and plays a vital role in the reproductive process. FSH can promote the development of male seminiferous epithelium, and stimulate spermatogenesis and sperm maturation; the function of FSH to women is to stimulate follicle development, promote follicle maturation, promote ovulation, stimulate multiple follicular developments, inhibit ovarian atresia, induce aromatase activity, stimulate Granulosa cell proliferation and induction of luteinizing hormone (LH) and prolactin (PRL) receptor production.

Urofollitropin product usage process

  During the menstrual cycle, the concentration of FSH in the blood and the amount of follicle-stimulating hormone excreted by urine vary with the cycle. After menopause, the excretion of follicle-stimulating hormones in blood and urine increases. Therefore, urinary gonadotropin (also known as menopausal urinary gonadotropin, menopausal gonadotropin, Ximeikang, or postmenopausal gonadotropin) is prepared from the urine of menopausal women, which contains follicle-stimulating hormone (FSH) and luteinizing hormone (LH ), and highly purified urinary follicle-stimulating hormone can be isolated.

  FSH is mainly used in anovulatory patients: including polycystic ovary syndrome patients who do not respond to clomiphene. In assisted reproductive technology, such as in vitro fertilization (IVF), gamete intrafallopian transfer (GIFT), and zygote intrafallopian transfer (ZIFT) in patients with superovulation.