Urofollitropin Products: Actions and Uses

　　The main physiological function of Urofollitropin (follicle stimulating hormone, FSH) in Urofollitropin (urine Follicle Stimulating Hormone, u-FSH) is to promote the growth and development of various cells of the follicle: to promote the differentiation of mesenchymal cells around the follicle cells into inner and outer layers of theca cells and Synthesize luteinizing hormone (LH) receptors; promote the proliferation of follicular granulosa cells and the activation of the aromatase system in granulosa cells to convert androgen into estrogen; promote the secretion of follicular fluid and gradually increase the size of follicle cells. 

     FSH is mainly aimed at infertility caused by ovulation disorders and is widely used in assisted reproductive technologies such as artificial insemination and test-tube baby. This product is different from HMG, only contains FSH, not LH. FSH mainly stimulates the growth, development, and maturation of follicles in the first half of menstruation, and an appropriate amount of LH is also required to participate. This product is suitable for anovulatory patients with insufficient FSH but not LH deficiency.