Extraction of urokinase: crude product extraction does not affect the safety of later pharmaceuticals

　　Urokinase is an enzyme protein isolated from healthy human urine or obtained from human kidney tissue culture. The urokinase can be extracted through the urine extraction process, and the urokinase can be used for the treatment of cardiovascular and cerebrovascular diseases and thrombus.

　　Urokinase is a thrombolytic substance. In Shanghai in the 1960s, some research institutes were already extracting urokinase. This method of extracting urokinase from the urine of healthy people has a scientific basis. Compared with streptokinase, which has the same effect, urokinase has no antigenicity and will not cause allergic reactions, but because it is extracted from urine, its cost is relatively high. Professor Feng said that the drug production process is affected by the technology, and the amount of the extracted drug is related to the advanced level of the technology. As for why male urine was chosen, Professor Feng said that it was mainly due to factors such as women's susceptibility to infection, and most of the students are in good health, so they are the ideal group for urine collection.

　　The crude urokinase obtained after collecting and processing the urine can be sold to pharmaceutical factories. The refining of the crude product is only the first step in the production of urokinase, which will not affect the safety of later-stage pharmaceuticals.