HMG works both in women and men.
1. The effect on women
HMG contains FSH and LH. For women, it can promote the development and
maturation of follicles, promote the secretion of estrogen from follicles, and
make the endometrium hyperplasia.
2. The effect on men
For men, it can promote the development of the seminiferous tubules of the
testis, promote the division of spermatogenic cells, and the maturation of
sperm. The combination of the two can reduce the sexual function of men with low
gonadotropins and have a spermatogenic effect.
3. Clinical effect
Clinically, it is mainly used in combination with chorionic gonadotropin
for primary or secondary amenorrhea caused by insufficient secretion of
gonadotropin, anovulatory oligomenorrhea, and infertility caused by it. It is
also used for primary or secondary amenorrhea, male sperm deficiency, and
ovarian function tests.
Therefore, HMG is mainly used clinically in assisted pregnancy techniques
such as IVF to promote follicle development so that more eggs can be obtained at
one time during egg retrieval; or it is used for luteal phase support therapy
after HMG therapy.
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