FSH has the functions of regulating menstrual cycle, ovulation and male
testicular function in human beings. It is commonly used in clinical treatment
of female infertility, insufficient secretion of male gonadotropins, and defects
of seminiferous tubules. In the human pituitary gland and in the urine of
menopausal and postmenopausal women, the content of both is higher, so it is
also the main source of FSH extraction.
The raw material for the production of
u-FSH, Human Menopausal Gonadotropin (HMG), mainly contains follicle-stimulating
hormone and luteotropic hormone (Luteotropic Hormone, LH). The ratio of FSH to
LH titers is approximately 1:1. The preparation of high-purity
urofollicle-stimulating hormone requires the removal of LH and other urinary
proteins from HMG, and the retention of high-purity single active component of
FSH.
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