[Drug Overview] UFO is extracted and purified from the urine of menopausal
women, and its active ingredient is FSH, which can promote the recruitment and
development of follicles. For women with non-primary ovarian failure,
urofollitropin can stimulate ovarian follicle development. In the absence of
endogenous LH peaks, when the monitoring results show that the follicles have
fully developed, human chorionic gonadotropin (HCG) should be injected after the
injection of this product to promote the full maturation of the follicles and
ovulation.
【Pharmacokinetics】Research reports of the same species abroad: In voluntary
healthy women with inhibited endogenous FSH, single-dose (225IU) and
multiple-dose (10I×7d) injection of Bravelle, the steady-state ratio of FSHCmax
and AUC can be determined It was seen that subcutaneous and intramuscular
injections of Bravelle were not bioequivalent. Steady-state ratios for multiple
doses of intramuscular Bravelle, cm, and AUC were 77.7% compared to 81.8% for
subcutaneous injections.
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