Urokinase is an enzyme protein isolated from healthy human urine or
obtained from human kidney tissue culture. It has the effect of dissolving
thrombus and is mainly used for the treatment of various thrombotic
diseases.
Precautions before taking urokinase:
Under what circumstances should urokinase be contraindicated?
This drug should be contraindicated in patients allergic to urokinase.
Urokinase should be contraindicated in patients with severe active
bleeding.
Urokinase is contraindicated in patients with acute visceral or
intracranial hemorrhage.
Urokinase is contraindicated in patients with cerebral hemorrhage within 2
months.
Urokinase is contraindicated in patients with severe hypertension.
Urokinase is contraindicated in patients undergoing major surgery or organ
biopsy.
Urokinase is contraindicated in women during childbirth.
Urokinase is contraindicated in patients with trauma within 10 days.
Patients with old cerebral infarction.
Patients with intracranial tumors, arteriovenous malformations, and
aneurysms.
Patients with abnormal blood coagulation.
Under what circumstances should urokinase be used with caution or
avoided?
Urokinase should be used with caution in patients who have recently
undergone cardiopulmonary bypass.
In patients with subacute infective endocarditis, urokinase should be used
with caution as prescribed by a doctor.
In patients with diabetic retinopathy, urokinase should be used with
caution as prescribed by a doctor.
Urokinase should be used with caution in patients with coagulation
disorders related to liver and kidney diseases.
The safety of the drug in pregnant women has not been established, so
urokinase should be used with caution according to the doctor's advice.
It is not clear whether urokinase is excreted in breast milk, so
breastfeeding women should use urokinase with caution according to the doctor's
advice.
Use with caution in people over 70 years old.
Urokinase and some drugs can interact and affect each other. If you are
using other medicines, be sure to inform your doctor before using urokinase, and
ask your doctor if you can take it and how to take it.
Drugs have adverse reactions. But don't refuse medication for fear of
adverse effects. You can read the drug instructions carefully or consult a
doctor to understand the adverse drug reactions of urokinase, and make certain
psychological preparations.
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