Human chorionic gonadotropin is a glycoprotein hormone produced by the
placenta, which is extracted from the urine of pregnant women. It can stimulate
gonadal activity, promote follicle maturation and ovulation in women, and
promote seminiferous duct function and Leydig cell activity in men to increase
androgen production, promote testicular descent and promote sperm
production.
Human chorionic gonadotropin is often used for sexual dysfunction, habitual
abortion, severe uterine bleeding, amenorrhea, infertility, cryptorchidism,
etc., but it is ineffective for cryptorchidism caused by anatomical lesions.
Chorionic gonadotropin shares the same alpha subunit structure as luteinizing
hormone (LH). It has biological activity and immune activity similar to LH, and
it needs a large dose of injection when it is used to stimulate follicle
maturation to simulate the LH peak before ovulation, thereby accelerating
follicle maturation and inducing ovulation. Commonly used to 10,000 U
intramuscular injection, most cases ovulate 36 ~ 48h after injection. If
conditions permit, use B-ultrasound to monitor follicular development. If
artificial insemination or trigger ovulation-guided sexual intercourse is
performed, it should be performed on the day of chorionic gonadotropin (HCG)
injection and (or) on the 2nd day, and B-ultrasound check again 48 hours later
to find out whether ovulation has occurred. If there is still no ovulation, it
is necessary to repeat the injection of HCG, and repeat the guidance of timely
sexual intercourse to improve the pregnancy rate.
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