Kangyuan Company is a professional Manufacturer of Hormone API,
specializing in production, which is your best choice. Here's an introduction to
the Urokinase Manufacturer.
Does urokinase have why pharmacological action?
Urokinase refers to an enzyme protein isolated from the urine of healthy
people or obtained from human kidney tissue culture. It is composed of two
molecular weights of 33000 (LMW- TKU-Pa) and 54000(HMW- TKU-Pa),
1. Urokinase acts directly on the endogenous fibrinolytic system and can
catalyze the lysis of plasminogen into plasminase.
Endogenous fibrinolytic system can not only degrade fibrin clots, but also
degrade fibrinogen, coagulation factor ⅴ and coagulation factor ⅷ in blood
circulation, so as to play the role of thrombolysis, and the newly formed
thrombi has a fast and good effect.
2. Urokinase can improve vascular ADP enzyme activity, inhibit ADP-induced
platelet aggregation and prevent thrombosis.
After intravenous infusion, plasminase activity in patients was
significantly increased; Plasminase activity returned to its original level a
few hours after withdrawal, but the reduction in plasma fibrin or fibrinogen
levels, and the increase in their degradation products, persisted for 12-24
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