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What are the pharmacological effects of Urokinase Manufacturer?

  Kangyuan Company is a professional Manufacturer of Hormone API, specializing in production, which is your best choice. Here's an introduction to the Urokinase Manufacturer.

  Does urokinase have why pharmacological action?

  Urokinase refers to an enzyme protein isolated from the urine of healthy people or obtained from human kidney tissue culture. It is composed of two molecular weights of 33000 (LMW- TKU-Pa) and 54000(HMW- TKU-Pa), respectively.

  1. Urokinase acts directly on the endogenous fibrinolytic system and can catalyze the lysis of plasminogen into plasminase.

  Endogenous fibrinolytic system can not only degrade fibrin clots, but also degrade fibrinogen, coagulation factor ⅴ and coagulation factor ⅷ in blood circulation, so as to play the role of thrombolysis, and the newly formed thrombi has a fast and good effect.

What are the pharmacological effects of Urokinase Manufacturer?

  2. Urokinase can improve vascular ADP enzyme activity, inhibit ADP-induced platelet aggregation and prevent thrombosis.

  After intravenous infusion, plasminase activity in patients was significantly increased; Plasminase activity returned to its original level a few hours after withdrawal, but the reduction in plasma fibrin or fibrinogen levels, and the increase in their degradation products, persisted for 12-24 hours.

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