Industry Information

What is the role of urokinase ?

  Urokinase can directly act on the endogenous fibrinolytic system and catalyze the lysis of plasminogen into fibrinolytic enzyme. Plasminolytic enzyme can not only degrade fibrinogen clots, but also degrade fibrinogen, coagulation factor 5 and coagulation factor 8 in blood circulation, so as to play the role of thrombolysis.

What is the role of urokinase ?

  What is the role of urokinase?

  Secondly, urokinase has a fast and good effect on newly formed thrombosis. Urokinase can also improve vascular ADP enzyme activity, inhibit ADP-induced platelet aggregation and prevent thrombosis.

  Urokinase in patients with intravenous drip, fibrinolytic enzyme activity increased significantly in the body, to a few hours after stopping drug, fibrinolytic enzyme activity to restore the original level, but plasma, fibrin and fibrinogen level is reduced, and the increase of their degradation products can last 12 to 24 hours, the thrombolytic effect of urokinase and drug dosage, dosing time window has obvious relevance.