Heparin sodium is mainly used for hemodialysis or hemofiltration to prevent
blood clotting and prevent thrombosis during extracorporeal circulation. The
drug is mainly used in hemodialysis for the prevention of blood clotting and the
treatment of deep vein thrombosis, unstable angina, and the prevention of
operation-related thrombosis.
Needs to be individualized dosage, in terms of dosage of the drug in the
application process may produce adverse reaction, can lead to bleeding,
especially large dose application that may lead to subcutaneous hematoma, may
also cause thrombocytopenia, skin necrosis, allergic reactions, rare is likely
to trigger transaminase lifts.
The drug also has contraindications during application. Patients with acute
gastroduodenal ulcer, cerebral hemorrhage, severe coagulation disease, and
septic endocarditis are prohibited to use. Thrombocytopenia in patients with
positive in vitro platelet aggregation test is contraindicated in patients with
central nervous system ocular or ear injury or surgical administration of
heparin. In the treatment of acute pulmonary thrombosis, local anesthetic drugs
should be used with caution.