The higher the human chorionic gonadotropin (HCG), the better

　　HCG, known in Chinese as human chorionic gonadotropin, is a hormone secreted by the placenta. It can be detected from the maternal serum 10 days after fertilization of the egg. It is the most sensitive method for the diagnosis of early pregnancy.

　　HICG plays a very important role in the growth and development of the fetus and the mother-to-be. HCG can promote the continued secretion of estrogen and progesterone in the corpus luteum of the maternal ovary, and promote the endometrium to receive embryo implantation. HCG can stimulate corpus luteum cells, maintain the life of corpus luteum, and make it develop into gestational corpus luteum.

　　The higher the HCG, the better?

　　Since HCG has so many functions, is the higher the HCG the better? Not really.

　　Maternal blood HCG changes significantly at different stages of pregnancy. In the absence of pregnancy, HCG<5IU/L, or not measured at all. On the 6th day after pregnancy, the villous trophoblast cells began to secrete trace amounts of HCG, and HCG was detected in the blood on the 10th day. After implantation, HCG levels in the pregnant mother's blood increased exponentially, peaking at 8 weeks, and then maintained slowly until 12 weeks. After 12 weeks, maternal blood HCG decreased rapidly. The concentration of HCG was only 10% of the peak in the middle and third trimester of pregnancy. Within 2 weeks after delivery, it returns to its pre-pregnancy level, which is undetectable.

　　Specific value can refer to: pregnancy 7 ~ 10 days >5IU/L, pregnancy 30 days >100IU/L, pregnancy 8 ~ 10 weeks is 50000 ~ 100000IU/L, pregnancy 14 weeks is 10000~20000IU/L.

　　Individual differences in HCG concentration are very large, that is to say, absolute differences in serum HCG between expectant mothers are very large. Therefore, after receiving the HCG report, expectant mothers should make a longitudinal comparison with their own gestational week to see the variation pattern of HCG, instead of comparing with their pregnant friends.

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