Do not understand sulfate skin element to see this article!

　　Dermatitin sulfate (DS) is a disaccharide polymer, which is the most widely distributed extracellularmatrix (ecm) glycosaminoglycan and the main component of proteoglycan. DS is a polysaccharide consisting of d-glucuronic acid and n-acetylgalactose, which are linked by the p-1, 4-glucosidine bond to form a repetitive disaccharide unit, and is sulfonated on the c-4 or c-6 hydroxyl group of n-acetylgalactose. Because of the sulfuric acid group, the whole cs molecule is highly electronegative and easy to covalently combine with proteins to form proteoglycan, which is also an important basis for its biological role. As an important component of connective tissue, DS has a variety of pharmacological and physiological functions and can be used as medicine and health food, mainly for osteoarthritis (oa) and coronary atherosclerotic heart disease.