Usage and dosage of ulinastatin injection
Note: the same medicine produced by different enterprises may have
different dosage due to different packaging specifications. Usage and dosage in
this article are for reference only. If you are not sure, refer to the
instructions on the medication or ask your doctor.
1. Acute pancreatitis and chronic recurrent pancreatitis: at the initial
stage, 1000 units were dissolved in 500ML 5% glucose injection or 0.9% normal
saline injection intravenously for 1 to 2 hours each time, 1-3 times a day, and
the dosage was reduced as the symptoms subsided;
2. Acute circulative failure, 100,000 units were dissolved in 500ml 5%
glucose injection or 0.9% normal saline injection intravenously, left for 1 to 2
hours each time, 1-3 times daily, or 100,000 units dissolved in 2ml 0.9% normal
saline injection, 1-3 times daily. And can be based on age, symptoms appropriate
increase or decrease.
The drug phase of ulinastatin injection
This product should not be mixed with gabeate or Gelobulin
preparations.
Pharmacological action of ulinastatin injection
This strain is a refined glycoprotein extracted from human urine and
belongs to protease inhibitor. It can inhibit trypsin and other trypsin
activities, and is often used in the treatment of pancreatitis. In addition, the
product has the functions of stabilizing lysosomal membrane, inhibiting the
release of lysosomal enzyme and inhibiting the production of myocardial
inhibitory factors, so it can be used in the rescue treatment of acute
circulatory failure
Methods of storage of ulinastatin injection
Keep in closed, cool and dry place.