Industry Information

Main functions of Human menopausal gonadotropin

  Human menopausal gonadotropin ACTS on the corpus luteum of menstruation and binds to the receptor on the cell membrane of corpus luteum to increase the corpus luteum into the corpus luteum of pregnancy. It increases the secretion of steroid hormones to maintain pregnancy until the trophoblast cells themselves produce enough progesterone to maintain the decidual membrane of pregnancy.

  Promoting the aromatization of androgens into estrogen and stimulating the formation of progesterone;

  Human menopausal gonadotropin has similar biological activity with luteinizing hormone (LH) and can induce ovulation in combination with human menopausal gonadotropin (HMG). It is of great significance to the treatment of male patients with pituitary joint defect, which can not only promote gonadal development and the secretion of male hormone, but also promote the development of secondary sexual characteristics.

  Human menopausal gonadotropin suppresses the immunity of lymphocytes and protects the trophoblastic layer from the mother's immune attack with a hormone barrier.

Main functions of Human menopausal gonadotropin

  Detection principle

  Immunological monoclonal antibody colloidal gold is often used in clinic. Two purplish red lines were positive and only one purplish red line was negative. This method is simple, fast and sensitive.

  Clinical significance

  Human menopausal gonadotropin detection is mainly used for:

  (1) early pregnancy diagnosis, generally in pregnancy after 35 ~ 40d, HCG level in 200ng/L above, 60 ~ 70d peak, commonly used test methods can show positive results;

  (2) abortion diagnosis and monitoring;

  (3) diagnosis of ectopic pregnancy;

  (4) diagnosis and observation of pregnancy trophoblast diseases.