The anti-inflammatory effect of ulinastatin

　　When the local inflammation, capillaries within the "chemokine" (ICAM - Ⅰ) in inflammatory peripheral region; This causes the accumulation of neutrophils in the blood. When neutrophils aggregate, they release "granulocyte elastase," an enzyme that destroys normal cells, activating and releasing inflammatory factors inside the cells. At the same time, granulocyte elastase also hydrolyzes the precursor of ulinastatin (IaI) into ulinastatin, which in turn binds to the hydrolytic enzyme, rendering it inactive.