Each woman is born with about 2 million primordial follicles. In childhood,
most primordial follicles gradually degenerate. At puberty, there are about
200,000 to 400,000 primordial follicles left in both ovaries.
Late one menstrual cycle before women of corpus luteum and the menstrual
cycle of early follicles, bilateral ovaries each will have a set of sinus
follicle (about 3 to 11) under the action of follicle-stimulating hormone (FSH)
together into the growth track, will other follicle atresia, raise, a process
known as ovarian function every female is different, raised the number of
follicles are also different. The growth of follicles after recruitment mainly
depends on gonadotropin, especially follicle stimulating hormone (FSH). Only
when the level of FSH reaches or exceeds a certain threshold can follicles
continue to grow.
In the natural cycle, around the 5th to 7th day of the menstrual cycle, the
follicle with the lowest threshold to FSH, that is to say, the follicle with the
most sensitive to FSH will preferentially develop into the dominant follicle,
while other follicles will gradually become atresia due to the low sensitivity
to FSH. You can collect more than one follicle in a cycle, but usually you end
up with only one follicle and occasionally you see two follicles mature and
ovulate, and that follicle is what we call the dominant follicle.
In the ovulation induction cycle, doctors will start to apply ovulation
induction drugs before the emergence of dominant follicles, usually on the 2nd
to 4th day of menstruation, and the most common is exogenous FSH, to promote the
growth of follicles that are going to be atresia, but the primordia follicles
that are not collected in this cycle will remain in a static state and will not
be affected. Therefore, ovulation induction does not exhaust the stored
follicles in the ovary in advance, but belongs to "waste utilization", which
enables the follicles that would otherwise be blocked to mature together and
obtain multiple mature eggs in a cycle as far as possible, so as to obtain as
many high-quality embryos as possible. It doesn't use up extra egg stock, so it
doesn't bring the menopause forward.
Generally speaking, if it is an ivf baby, in order to ensure the success
rate of pregnancy, sometimes more than 10 follicles will be produced at one
time, but the maximum number of fertilized eggs will be implanted, that is, the
maximum number of twins. And even that doesn't make you prematurely
menopausal.
So, when you cause infertility due to ovulation disorder, you can
completely rest assured to listen to the doctor's arrangement, the use of
ovulation drugs to help you realize the dream of motherhood as soon as
possible.