Hemodialysis is one of the methods of renal replacement therapy for chronic
renal failure. To complete hemodialysis treatment, an effective vascular access
must be established, which can be said to be the lifeline of patients. With the
increasing number of patients with long-term catheterization on hemodialysis,
the incidence of catheter dysfunction also increases gradually.
Recently, the blood dialysis room of the fourth people's hospital of hulun
buir (former agricultural reclamation hospital) sent the backbone of the
department to the higher hospital to learn urokinase embolization, and conducted
many exchanges and discussions in the general department.
Urokinase is an anti - fibrinolytic agent with good thrombolytic effect and
low bleeding rate. Urokinase embolization is to inject the appropriate ratio of
urokinase solution into the arteriovenous end of the catheter according to the
volume of the lumen so that urokinase gradually permeates into the fibrin of the
inner wall of the catheter and around the catheter to activate plasminogen and
For patients with hemodialysis catheterization, the regular application of
urokinase prophylactic intra-catheter thrombolysis therapy can maintain the
long-term patency of the catheter and meet the blood volume, solutes clearance
index and indentation time required for dialysis adequacy, so as to enhance the
dialysis effect and reduce the economic burden and mental pressure. At the same
time, this technique also makes up for the shortcomings of indwelling catheter
thrombolytic therapy in the department for many years.